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Bernhard Zabel Selected Research

mitochondrial RNA-processing endoribonuclease (RNAse MRP)

12/2021Uncovering pathways regulating chondrogenic differentiation of CHH fibroblasts.
1/2019The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion.
1/2017Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic differentiation.
11/2005Severely incapacitating mutations in patients with extreme short stature identify RNA-processing endoribonuclease RMRP as an essential cell growth regulator.

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Bernhard Zabel Research Topics

Disease

7Cartilage-hair hypoplasia
12/2021 - 11/2005
3Dwarfism
01/2019 - 09/2009
3Hypertrophy
01/2017 - 12/2005
3Neoplasms (Cancer)
05/2006 - 11/2003
2Achondroplasia
02/2015 - 12/2006
2Joint Diseases (Joint Disease)
08/2012 - 11/2011
2Omani type Spondyloepiphyseal dysplasia
10/2010 - 06/2008
2Joint Dislocations
10/2010 - 06/2008
2Larsen Syndrome
10/2010 - 06/2008
2Ovarian Neoplasms (Ovarian Cancer)
09/2005 - 11/2003
1Inborn Genetic Diseases (Disease, Hereditary)
12/2021
1Achondrogenesis
02/2019
1Sitosterolemia
01/2016
1Corneal Injuries
06/2015
1Megalocornea
06/2015
1Thanatophoric Dysplasia (Dwarfism, Thanatophoric)
02/2015
1Maroteaux type Acromesomelic dysplasia
02/2015
1Pain (Aches)
08/2013
1Hyperostosis corticalis deformans juvenilis
08/2013
1Hypocalcemia
08/2013
1Peripheral Nervous System Diseases (PNS Diseases)
08/2012
1of childhood progressive pseudorheumatoid Arthropathy
08/2012
1Pseudoachondroplasia
01/2012
1Brachyolmia
11/2011
1Hereditary Sensory and Motor Neuropathy (Dejerine Sottas Disease)
11/2011
1Metatropic dwarfism
11/2011
1Spinal Muscular Atrophy (Progressive Muscular Atrophy)
11/2011
1Kozlowski type Spondylometaphyseal dysplasia
11/2011
1Arachnodactyly
07/2011
1Marfan Syndrome (Marfan's Syndrome)
07/2011
1Intellectual Disability (Idiocy)
11/2010
1Epilepsy (Aura)
11/2010
1Desbuquois syndrome
10/2010
1Diastrophic dysplasia
06/2008
1Syndactyly (Polysyndactyly)
03/2008
1Telecanthus
03/2008
1Opitz-Kaveggia syndrome
08/2007
1Constipation
08/2007
1Pakistani Type Spondyloepimetaphyseal Dysplasia
05/2007
1Osteochondrodysplasias (Spondyloepiphyseal Dysplasia)
02/2007
1Anauxetic dysplasia
11/2005
1Ovarian Epithelial Carcinoma
09/2005
1Wilms Tumor (Wilm's Tumor)
03/2005
1Beckwith-Wiedemann Syndrome (Exomphalos Macroglossia Gigantism Syndrome)
03/2005
1Torrance Type Platyspondylic Lethal Skeletal Dysplasia
02/2005
1Brachydactyly
08/2004
1Acromesomelic dysplasia
07/2004

Drug/Important Bio-Agent (IBA)

4mitochondrial RNA-processing endoribonuclease (RNAse MRP)IBA
12/2021 - 11/2005
4Proteins (Proteins, Gene)FDA Link
08/2012 - 03/2005
3Messenger RNA (mRNA)IBA
01/2019 - 09/2005
3RNA (Ribonucleic Acid)IBA
01/2017 - 12/2005
2Small Nucleolar RNA (snoRNA)IBA
12/2021 - 01/2019
2Calcium Channels (Calcium Channel)IBA
08/2012 - 11/2011
2Cartilage Oligomeric Matrix ProteinIBA
01/2012 - 02/2007
2Carbohydrate SulfotransferasesIBA
10/2010 - 06/2008
2FilaminsIBA
10/2010 - 08/2007
2CyclinsIBA
03/2008 - 11/2005
2CollagenIBA
02/2005 - 08/2004
1Polysaccharides (Glycans)IBA
02/2019
1Proteoglycans (Proteoglycan)IBA
02/2019
1Ribonucleases (Ribonuclease)IBA
01/2019
1Mitochondrial RNAIBA
01/2019
1RNA Precursors (Precursor, mRNA)IBA
01/2017
1Long Noncoding RNAIBA
01/2017
1Protein Subunits (Protein Subunit)IBA
01/2017
1LipidsIBA
01/2016
1Phytosterols (Plant Sterols)IBA
01/2016
1chordinIBA
06/2015
1atrial natriuretic factor receptor BIBA
02/2015
1C-Type Natriuretic Peptide (Peptide, C-Type Natriuretic)IBA
02/2015
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
02/2015
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
02/2015
1atrial natriuretic factor receptor CIBA
02/2015
1NTproCNPIBA
02/2015
1DenosumabFDA Link
08/2013
1RANK LigandIBA
08/2013
1CalciumIBA
08/2013
1Collagen Type IXIBA
01/2012
1Matrilin ProteinsIBA
01/2012
1Fibrillin-1IBA
07/2011
1Nonsense Codon (Nonsense Mutation)IBA
11/2010
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
11/2010
1SulfotransferasesIBA
10/2010
1ChondroitinIBA
10/2010
1SilverIBA
09/2009
1Oligonucleotide ProbesIBA
06/2009
1DNA (Deoxyribonucleic Acid)IBA
06/2009
1Chondroitin Sulfate ProteoglycansIBA
06/2008
1Sulfate TransportersIBA
06/2008
1N-acetyltalosaminuronic acid (NAT)IBA
05/2007
1Cysteine (L-Cysteine)FDA Link
12/2006
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
12/2006
1Untranslated RNA (Noncoding RNA)IBA
10/2006
14-epianhydrotetracycline (anhydrotetracycline)IBA
05/2006
1CytokinesIBA
12/2005
1Ribosomal RNAIBA
11/2005
1ChromatinIBA
03/2005
1Insulin-Like PeptidesIBA
03/2005
1Collagen Type II (Type II Collagen)IBA
02/2005

Therapy/Procedure

3Therapeutics
06/2015 - 11/2003